藥物警訊（藥師週刊 第1674期）

Maalox Total Relief and Maalox Liquid Products: Medication Use Errors
Audience: Consumers, Healthcare professionals
FDA notified consumers and healthcare professionals about reports of serious medication errors involving consumers who used Maalox Total Relief when they had intended to use a Maalox liquid antacid product. Maalox Total Relief and the traditional Maalox products are both liquid medications available without a prescription, but are not interchangeable and are intended to treat different medical conditions. Maalox Total Relief is an upset stomach reliever and anti-diarrheal medication, while traditional Maalox liquid products Maalox Advanced Regular Strength and Maalox Advanced Maximum Strength are antacids.
Maalox Total Relief is not appropriate for individuals who want to use an antacid, since it contains the active ingredient bismuth subsalicylate which is chemically related to aspirin and may cause serious adverse effects such as bleeding. Maalox Total Relief should not be used in people who have or have a history of gastrointestinal ulcers or a bleeding disorder. It also should not be taken by children and teens if they are recovering from a viral infection, nor by individuals who are taking certain medications including: oral antidiabetic drugs (OADs), anticoagulation (thinning the blood) drugs such as warfarin (Coumadin) and clopidogrel (Plavix), non-steroidal anti-inflammatory drugs (NSAIDS), and other anti-inflammatory drugs.?
The Drug Safety Communication contains additional information for consumers and healthcare professionals, as well as product label photos.
Read the complete MedWatch 2010 Safety summary, including links to the Drug Safety Communication and FDA news release, at:
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHuma...

FDA發佈藥物安全警訊，通知消費者和醫護人員關於嚴重用藥錯誤的報告。許多原先欲使用Maalox 液體制酸劑相關產品(Maalox liquid antacid product)的消費者卻誤用成Maalox Total Relief。Maalox Total Relief和傳統的Maalox產品都是液體的非處方藥藥品，適應症各不相同並不能互相替換使用。Maalox Total Relief為緩解腸胃不適和治療腹瀉的藥品，而Maalox液劑產品(如：Maalox Advanced Regular Strength和Maalox Advanced Maximum Strength)則都是制酸劑。
Maalox Total Relief不適合用於想要使用制酸劑的病人，因為該藥品含有與阿斯匹靈(aspirin)化學結構相關的主成份，bismuth subsalicylate，所以可能會引起嚴重的副作用，例如：出血。Maalox Total Relief不建議用於有腸胃道潰瘍或出血病史的病人，也不建議用於曾受病毒感染而剛復原的小孩或青少年。有使用口服降血糖藥物、抗凝血劑，例如：warfarin (Coumadin)和clopidogrel(Plavix)、非類固醇止痛消炎藥和其他的止痛消炎藥的病人也應避免使用Maalox Total Relief。
藥物安全警訊相關連結中附有藥品的資料和產品的圖片以提供醫護人員和消費者參考。

相關訊息請參考FDA網址:
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm200672.htm
[Posted 02/17/2010]

資料來源：美國FDA之藥物安全警訊
資料提供：台大醫院藥劑部